Wize Guyz Grille

Wize Guyz Grille is a beloved family-owned restaurant serving Western North Carolina with big flavor and no shortcuts. Located at 68 Big Cove Rd Suite 8 in Cherokee, just minutes from the Great Smoky Mountains National Park, this flagship location has become the go-to destination for locals and tourists seeking authentic American comfort food. The menu features juicy half-pound Black Angus smash burgers piled high with crispy bacon, cheddar, house pickles, and their legendary Wize sauce — a fan favorite that keeps customers coming back for more. Their flavor-loaded wings come in eight distinctive sauces ranging from sweet honey gold to face-melting inferno, always served crispy and fresh. Pizza lovers will appreciate their authentic 16-inch New York-style pies, hand-stretched with house-made sauce and real mozzarella, available by the slice or whole. The restaurant operates Monday through Thursday 11 AM to 9 PM, Friday and Saturday 11 AM to 10 PM, and Sunday 12 PM to 8 PM. With over 2,600 Google reviews praising everything from their chili cheese fries to their meat lovers pizza, Wize Guyz Grille has earned its reputation as one of the best restaurants in Cherokee. Owned by Thomas and Norma, the restaurant is part of the Bynum Food Group family alongside Mabel's Kitchen, Ice Cream Station & More, and All Fried Up.