Regina Pizzeria

Regina Pizzeria in Hyannis brings nearly a century of authentic Italian pizza-making tradition to Cape Cod, continuing the legendary legacy that began in Boston's North End in 1926. This iconic establishment, founded by the Polcari Family, has earned its reputation as America's premier brick oven pizzeria, crowned #1 in the country by TripAdvisor and voted Boston's Best Pizza by BIG 7 Travel. The restaurant's signature thin-crust pizza features a secret century-old dough recipe aged to perfection, topped with a light yet spicy tomato sauce hinting of aged Romano cheese, and covered with specialty aged whole milk mozzarella that creates that distinctive Regina flavor profile. The Caprese Pizza, a seasonal favorite featuring garden-fresh heirloom tomatoes and fresh mozzarella on aged Regina dough with garlic sauce, has become a must-try for discerning pizza lovers. Located on Iyannough Road in the heart of Hyannis, this Cape Cod location offers the same exceptional quality that has made Regina the official pizza of the Boston Red Sox. The restaurant features a loyalty program offering $5 rewards after your first visit, with points converting at a straight rate of $1 equals one point, and special birthday month perks. Whether you're a local Cape Cod resident or vacationing on the Massachusetts coast, Regina Pizzeria delivers an authentic Italian dining experience steeped in three generations of family tradition and uncompromising quality.