Cafe 251

Café 251 is a popular downtown Indianapolis cafe located at 251 N Illinois St in the heart of Indy's business district. This casual, quick-service cafe has become a go-to spot for downtown workers, professionals, and visitors seeking delicious breakfast and lunch options without the wait. The menu features an impressive variety of made-to-order deli sandwiches served on sourdough, marble rye, or 9-grain wheat bread, including classics like the Club, B.L.T., and Roast Beef, as well as hot sandwiches such as the Cuban, Chicken Melt, and Italian Beef. Guests can also choose from hearty wraps including the popular Chipotle Chicken and Chicken Caesar varieties. The lunch menu expands to include fresh salads like the BBQ Chicken, Applewood, Chicken Cobb, and build-your-own options, along with satisfying bowls, burritos, and loaded baked potatoes. Café 251 offers convenient boxed lunches complete with a sandwich, chips, and cookie—perfect for office meetings or on-the-go dining. Their catering services include breakfast platters, deli sandwich and wrap platters, and group packages. Open Monday through Friday for breakfast and lunch, this Indianapolis cafe combines quality ingredients, generous portions, and friendly service in a welcoming atmosphere just steps from Monument Circle.